S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID
(+)-Alpha-Methyl-4-Carboxyphenylglycine
CAS: 150145-89-4
Molecular Formula: C10H11NO4
S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID - Names and Identifiers
S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID - Physico-chemical Properties
| Molecular Formula | C10H11NO4 |
| Molar Mass | 209.2 |
| Solubility | 0.1 M NaOH: 15mg/mL |
| Appearance | solid |
| Color | White to off-white |
| Storage Condition | Store at RT |
| In vitro study | (S)-MCPG (100 μM) has no detectable effects on basal spine formation or elimination mechanisms in WT slice cultures. (S)-MCPG prevents the increase in spine turnover triggered by TBS and interferes with the mechanisms of activity-dependent spine stabilization in Hippocampal slice cultures. |
S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29224985 |
S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.78 ml | 23.901 ml | 47.801 ml |
| 5 mM | 0.956 ml | 4.78 ml | 9.56 ml |
| 10 mM | 0.478 ml | 2.39 ml | 4.78 ml |
| 5 mM | 0.096 ml | 0.478 ml | 0.956 ml |
Last Update：2024-01-02 23:10:35
S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID - Reference Information
| biological activity | (S)-MCPG (( )-MCPG) it is a potent class I/II metabotropic glutamate receptor (mGluRs) antagonist and is the active isomer of (RS)-MCPG (HY-100371). (S)-MCPG can be used to study the role of mGluRs in spatial learning. |
| Animal Model: | Male Lister-Hooded rats in the learning of the Morris water maze |
| Dosage: | 20 μg |
| Administration: | Intraventricular injection; 20 μg; 4 days |
| Result: | Impaired the performance of rats in the spatial version of the Morris water maze, but 1/10 of this dose did not. |
Last Update：2024-04-09 20:52:54
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View History
S(+)-ALPHA-AMINO-4-CARBOXY-ALPHA-METHYL-BENZENEACETIC ACID
3-羟基-5-三氟甲基-2-甲酸甲酯噻吩
2-甲基-5-溴嘧啶-4-甲酸
2-Thiazolecarboxamide, 4-methylthio- (6CI)
ALUMINIUMZIRCONIUMTETRACHLOROHYDRATE
1-苄基氮杂环丁烷-2-羧酸乙酯
异风藤奎醇A
圣草酚-7-O-葡萄糖醛酸苷
2.2.2-三氟乙酸胺
Z-L-VALINE HYDROXYSUCCINIMIDE ESTER
3-羟基-5-三氟甲基-2-甲酸甲酯噻吩
2-甲基-5-溴嘧啶-4-甲酸
2-Thiazolecarboxamide, 4-methylthio- (6CI)
ALUMINIUMZIRCONIUMTETRACHLOROHYDRATE
1-苄基氮杂环丁烷-2-羧酸乙酯
异风藤奎醇A
圣草酚-7-O-葡萄糖醛酸苷
2.2.2-三氟乙酸胺
Z-L-VALINE HYDROXYSUCCINIMIDE ESTER